Mice grow monkey sperm
By Lucy Sherriff
Posted: 05/02/2004 at 17:14 GMT
A team of US scientists has created viable monkey sperm in mice, using transplanted testicular tissue.* From the date of the transplant, it took seven months for live sperm to be produced.
Amusing as the image of a mouse with monkey balls on its back is, the research is being done for a purpose, not just the entertainment of the faculty staff. The technique will initially be used to reduce the amount of experimentation on primates, but could be used to help conserve endangered animal populations. Researchers also say that it is possible that human sperm could be grown in the same way – a novel, if controversial, approach to human fertility treatment.
The testis skin from a young rhesus macaque monkey was implanted under the skin on the back of a mouse with a depleted immune system. This minimised the likelihood that the tissue would be rejected. The mouse was also castrated, so that it would produce a higher level of the hormone that switches on sperm production. This causes the transplanted skin to grow faster.
The next step, say researchers, is a trial with domestic cats as a prelude to work with big cats that only rarely survive to reproductive age in captivity.
Read the rest
here.